The 12 Sector Collaboration Series places the Strategic Prevention Framework (SPF) into the context of the 12 Sectors of Coalition Building: Youth, Parents, Business, Media, Schools, Youth-serving Organizations, Law Enforcement, Faith-based organizations, Civic or Volunteer groups, Healthcare professionals, State or Local agencies, and Substance Abuse Agencies. Each sector is examined for how it can be incorporated within each step of the SPF, assess current coalition engagement level of each sector, building capacity to increase engagement and overcome barriers, and learn from the lived experience from a guest panel.